<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 3; Issue 3</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(May-Jun, 2022)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Schmidt’s Disease: A Case Report</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>6</LastPage> <AuthorList> <Author> <FirstName>Amani</FirstName> <LastName>Al-rifai</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Joyce</FirstName> <LastName>Chbib</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Ghassan</FirstName> <LastName>Kdouh</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>The Polyglandular autoimmune syndromes (PGA) consists of immune dysfunction affecting two or more endocrine glands and other non-endocrine organs. There are PGA I, PGA II and PGA III. The second type involves dysfunction of the adrenal gland, namely Addison’s disease plus either autoimmune thyroiditis or type I Diabetes Mellitus. We report the case of a 21 year old female known to have Hashimoto disease who has presented with generalized fatigue and abdominal pain induced by an adrenal insufficiency onset. She was diagnosed with PGA II and treated with hydrocortisone and levothyroxine to which her condition quickly responded and eventually improved.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Polyglandular Autoimmune Syndromes,Schmidt’s Disease,Endocrine Glands,Diabetes Mellitus</Keywords> <URLs> <Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=13707&title=Schmidt’s Disease: A Case Report</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Bello MO and Garla VV. Polyglandular Autoimmune Syndrome Type I. [Updated 2021 Jul 21]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022. Freeland ZK, Lueking R, Tsai-Nguyen G, Pan T, Mora A Jr. Adrenal crisis and autoimmune polyglandular syndromes. Proc (Bayl Univ Med Cent) 2017; 30: 427-428. Hansen MP, Wunderlich SA, Storz SM, Matheis N, Knuf M, Kahaly GJ. Das polyglanduland;auml;re Autoimmunsyndrom--Lebensqualitand;auml;t und familiand;auml;re Beteiligung [The polyglandular autoimmune syndrome--quality of life and family clustering]. Dtsch Med Wochenschr 2014; 139: 1876-1882. Husebye ES, Anderson MS, Kand;auml;mpe O. Autoimmune Polyendocrine Syndromes. N Engl J Med 2018; 378: 1132-1141. Kahaly GJ. Polyglandular autoimmune syndromes. Eur J Endocrinol 2009; 161: 11-20. Sonthalia N, Ray S, Maiti A, Maitra S. Autoimmune Polyglandular Syndrome Type II Presenting as an Endocrine Emergency: A Case Report. Oman Med J 2013; 28: e048. Sperling MA, Angelousi A, Yau M. Autoimmune Polyglandular Syndromes. 2021 Apr 10. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dhatariya K, Dungan K, Hershman JM, Hofland J, Kalra S, Kaltsas G, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrand;egrave;re B, Levy M, McGee EA, McLachlan R, Morley JE, New M, Purnell J, Sahay R, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905375. Web-Links 1. https://www.addisonsdisease.org.uk/adrenal-insufficiency-due-to-autoimmune-polyglandular-syndrome-aps-type-i-and-type-ii</References> </References> </Journal> </Article> </ArticleSet>