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<JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
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<Volume-Issue>Volume 1; Issue 1, (Jan-Jun,2021)</Volume-Issue>
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<IssueTopic>Multidisciplinary</IssueTopic>
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<Season>Archives of Medical and Clinical Research</Season>
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<Month>11</Month>
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<ArticleType>Medical and Clinical Research</ArticleType>
<ArticleTitle>Topical Treatment of Cutaneous Leishmaniasis: A Case Treated with A Glucantime-Based Lotion Experienced in Ecuador and A Mini Review</ArticleTitle>
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<ArticleLanguage>English</ArticleLanguage>
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<Author>
<FirstName>Yoshihisa</FirstName>
<LastName>Hashiguchi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Lenin V.</FirstName>
<LastName>Nieto</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Nancy C.</FirstName>
<LastName>Villegas</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Eduardo A.</FirstName>
<LastName>Gomez</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Hirotomo</FirstName>
<LastName>Kato</LastName>
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<Abstract>A 1.5-year-old male patient living in a remote community in the southeast of Manab__ampersandsigniacute; province of Ecuador was diagnosed as cutaneous leishmaniasis (CL) caused by Leishmania (Viannia) guyanensis. He was treated with a lotion, meglumine antimoniate Glucantime plus Merthiolate chloride, applying four to five times a day during eight weeks. The complete cure of lesion was obtained. This childhood-CL case did not respond against systemic therapy with Glucantime for the first cycle of regimen administered before the current topical treatment. Although systemic administration of pentavalent antimonials still remain as the first choice of treatment, it may often cause severe side effects, in addition to various disadvantages, such as painful injections, long-term regimens, difficulty to access health centers for patients living in remote/mountainous endemic areas. Therefore, as the alternatives, effective, easy-applicable and patient-compliant treatment is urgent need, especially for childhood-CL patients, who are highly vulnerable for toxic, systemic administrations of the drug. The current Glucantime plus Merthiolate lotion could be recommended as a future topical therapy of CLs, because of several advantages, easy-application, already-used drug as systemic therapy for the disease for a long time, more than 70 years.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Cutaneous Leishmaniasis,Topical Treatment,Meglumine Antimoniate,Ecuador</Keywords>
<URLs>
<Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=15233&title=Topical Treatment of Cutaneous Leishmaniasis: A Case Treated with A Glucantime-Based Lotion Experienced in Ecuador and A Mini Review</Abstract>
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<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
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<ReferenceslastPage>19</ReferenceslastPage>
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