<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 1; Issue 4</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Jul-Aug, 2020)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Hemophagocytic Lymphohistiocytosis Associated with Sarcoidosis: A Case Report and Review of the Literature</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>8</LastPage> <AuthorList> <Author> <FirstName>Korkor</FirstName> <LastName>Sackey</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Dana</FirstName> <LastName>Angelini</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal inflammatory syndrome characterized by histiocyte proliferation and hemophagocytosis. Primary HLH primarily occurs in children and is caused by genetic mutations. Secondary HLH, more often seen in adults, occurs as a result of infections, malignancies or rarely rheumatic diseases. HLH secondary to sarcoidosis is rare. We present a case of HLH associated with recently diagnosed sarcoidosis in a 61-year-old female.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Hemophagocytic lymphohistiocytosis,Sarcoidosis,Histiocyte proliferation</Keywords> <URLs> <Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=8093&title=Hemophagocytic Lymphohistiocytosis Associated with Sarcoidosis: A Case Report and Review of the Literature</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Abughanimeh O, Qasrawi A, Abu Ghanimeh M. Hemophagocytic Lymphohistiocytosis Complicating Systemic Sarcoidosis. Cureus 2018; 10:e2838 Bartholo TP, Pugliese JG, Mafort TT, Silva VL, Costa CH, Rufino R. Hemphagocytic syndrome due to pulmonary sarcoidosis. Bras Pneumol 2012; 38: 666-671 Atteritano M, David A, Bagnato G, Beninati C, Frisina A, Iaria C, Bagnato G, Cascio A. Hemophagocytic syndrome in rheumatic patients: A systematic review. Eur Rev Med Pharmacol Sci 2012; 16: 1414-1424 Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, Atsumi T, Koike T. Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology (Oxford) 2008; 47: 1686-1691. Dhote R, Simon J, Papo T, Detournay B, Sailler L, Andre MH, Dupond JL, Larroche C, Piette AM, Mechenstock D, Ziza JM, Arlaud J, Labussiere AS, Desvaux A, Baty V, Blanche P, Schaeffer A, Piette JC, Guillevin L, Boissonnas A, Christoforov B. Reactive hemophagocytic syndrome in adult systemic disease: report of twenty-six cases and literature review. Arthritis Rheum 2003; 49: 633-639. Henter JI, Horne A, Arico M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007; 48: 124-131. James WE, Koutroumpakis E, Saha B, Nathani A, Saavedra L, Yucel RM, Judson MA. Clinical Features of Extrapulmonary Sarcoidosis Without Lung Involvement. Chest 2018; 154: 349-356.</References> </References> </Journal> </Article> </ArticleSet>