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<Journal>
<PublisherName>jmedicalcasereports</PublisherName>
<JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Volume 1; Issue 6</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>(Nov-Dec, 2020)</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>Medical Case Reports</ArticleType>
<ArticleTitle>Deep Vein Thrombosis and Subsequent Pulmonary Embolism in A Patient Recovered from COVID-19</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1</FirstPage>
<LastPage>7</LastPage>
<AuthorList>
<Author>
<FirstName>Elena</FirstName>
<LastName>Kordzaya</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Oleg</FirstName>
<LastName>Dukhin</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Polina</FirstName>
<LastName>Golovina</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Darya</FirstName>
<LastName>Vorobyeva</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Elena</FirstName>
<LastName>Maryukhnich</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Polina</FirstName>
<LastName>Savvinova</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Elena</FirstName>
<LastName>Vasilieva</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Alexander</FirstName>
<LastName>Shpektor</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
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<DOI/>
<Abstract>A 45-year-old female patient with a previous SARS-CoV2 pneumonia suddenly presented with pain, swelling and cyanosis of the left leg, and severe dyspnea. Extensive deep vein thrombosis of the left leg and bilateral pulmonary embolism were diagnosed. The patient received standard treatment according to ESC 2019 Guidelines on Acute Pulmonary Embolism (Konstantinides et al., 2019). A study of the patient’s cytokine profile was carried out, according to which an increase in several pro-inflammatory cytokines was detected. After a 3-week follow-up, partial recanalization of the deep veins of the left leg was revealed.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>COVID-19,Pulmonary embolism,Cytokines,Thrombosis</Keywords>
<URLs>
<Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=8314&title=Deep Vein Thrombosis and Subsequent Pulmonary Embolism in A Patient Recovered from COVID-19</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
<References>Atallah B, Mallah SI, AlMahmeed W. Anticoagulation in COVID-19. Eur Hear Journal Cardiovasc Pharmacother 2020; 6: 260-261.
Bertin FR, Rys RN, Mathieu C, Laurance S, Lemariand;eacute; CA, Blostein MD. Natural killer cells induce neutrophil extracellular trap formation in venous thrombosis. J Thromb Haemost 2019; 17: 403-414.
Bester J and Pretorius E. Effects of IL-1and;beta;, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity. Sci Rep 2016; 6: 1-10.
Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol 2020; 75: 2950–2973.
Christiansen SC, Nand;aelig;ss IA, Cannegieter SC, Hammerstrand;oslash;m J, Rosendaal FR, Reitsma PH. Inflammatory Cytokines as Risk Factors for a First Venous Thrombosis: A Prospective Population-Based Study. PLoS Med 2006; 3: e334.
Cohen AT, Harrington RA, Goldhaber SZ, Hull RD, Wiens BL, Gold A, Hernandez AF, Gibson CM. Extended thromboprophylaxis with betrixaban in acutely ill medical patients. N Engl J Med 2016; 375: 534-544.
Cohen AT, Spiro TE, Spyropoulos AC, Desanctis YH, Homering M, Band;uuml;ller HR, Haskell L, Hu D, Hull R, Mebazaa A, Merli G. D-dimer as a predictor of venous thromboembolism in acutely ill, hospitalized patients: A subanalysis of the randomized controlled MAGELLAN trial. J Thromb Haemost 2014; 12: 479-487.
Connors JM and Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood 2020.
Gupta N, Zhao YY, Evans CE. The stimulation of thrombosis by hypoxia. Thromb Res 2019; 181: 77-83.
Halici B, Ulasli SS, Gand;uuml;nay E, Nural S, Sen S, Akar O, Celik S, Unlu M. Assessment of inflammatory biomarkers and oxidative stress in pulmonary thromboembolism: Follow-up results. Inflammation 2014; 37: 1186-1190.
Kalinskaya A, Dukhin O, Molodtsov I, Maltseva A, Sokorev D, Elizarova A, Sapozhnikova O, Glebova K, Stonogina D, Shakhidzhanov S, Nikonov E. Dynamics of coagulopathy in patients with different COVID-19 severity. MedRxiv 2020: 2020.07.02.20145284.
Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimand;eacute;nez D, Kucher N. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Respir J 2019; 54: 1901647.
Nosaka M, Ishida Y, Kimura A, Kuninaka Y, Inui M, Mukaida N, Kondo T. Absence of IFN-and;gamma; accelerates thrombus resolution through enhanced MMP-9 and VEGF expression in mice. J Clin Invest 2011; 121: 2911-2920.
Phillippe HM. Overview of venous thromboembolism. Am J Manag Care 2017; 23: S376–S382.
Rico-Mesa JS, Rosas D, Ahmadian-Tehrani A, White A, Anderson AS, Chilton R. The Role of Anticoagulation in COVID-19-Induced Hypercoagulability. Curr Cardiol Rep 2020; 22.
Rothan HA and Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109: 102433.
Spiezia L, Boscolo A, Poletto F, Cerruti L, Tiberio I, Campello E, Navalesi P, Simioni P. COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure. Thromb Haemost 2020; 120: 998–1000.
Spyropoulos AC, Levy JH, Ageno W, Connors JM, Hunt BJ, Iba T, Levi M, Samama CM, Thachil J, Giannis D, Douketis JD. Scientific and Standardization Committee Communication: Clinical Guidance on the Diagnosis, Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID?19. J Thromb Haemost 2020a: jth.14929.
Spyropoulos AC, Lipardi C, Xu J, Peluso C, Spiro TE, De Sanctis Y, Barnathan ES, Raskob GE. Modified IMPROVE VTE Risk Score and Elevated D-Dimer Identify a High Venous Thromboembolism Risk in Acutely Ill Medical Population for Extended Thromboprophylaxis. TH Open 2020b; 04: e59–e65.
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost 2020a; 18: 844–847.
Thachil J, Tang N, Gando S, Falanga A, Levi M, Clark C, Iba T, Cattaneo M. Type and dose of heparin in COVID?19. J Thromb Haemost 2020.
Zhang Y, Zhang Z, Wei R, Miao X, Sun S, Liang G, Chu C, Zhao L, Zhu X, Guo Q, Wang B. IL (Interleukin)-6 Contributes to Deep Vein Thrombosis and Is Negatively Regulated by miR-338-5p. Arterioscler Thromb Vasc Biol 2020; 40: 323-334.</References>
</References>
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