<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 3; Issue 5</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Sep-Oct, 2022)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Acute Spinal Cord Dysfunction Following COVID-19 Infection: A Case Report</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>7</LastPage> <AuthorList> <Author> <FirstName>Luca</FirstName> <LastName>Braglia</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Gabriele</FirstName> <LastName>Vandelli</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Angioletta</FirstName> <LastName>Manenti</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Stefano</FirstName> <LastName>Sacchi</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Here, we describe a 44-year-old female that developed abrupt symptomatology, including lower-limb paralysis with sensory involvement at the T12 level, two weeks after the resolution of COVID-19 bilateral pneumonia. Based on the neurological symptoms and the neurophysiological investigations, a clinical diagnosis of thoracic spinal cord dysfunction was made. However, all the complementary tests performed showed normal results. In particular, repeated MRIs showed no alterations; the cerebrospinal fluid analysis showed normal results: the CT scan of the brain was normal and the CT scan of the abdominal and thoracic aorta showed a normal size and course. Cases of spinal cord involvement have rarely been described, in which the MRIs never revealed cord signaling changes. We hypothesize that a small vessel spinal cord stroke might explain the pathogenesis and the absence of changes detectable on an MRI along with the patient__ampersandsign#39;s modest recovery during the long follow up. However, it cannot be excluded that the severe clinical course of SARS-CoV-2 infection, may suggest other different etiologies that could be related to prolonged hospitalization.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>COVID-19,Spinal Cord Dysfunction,Lower-limb Paresis</Keywords> <URLs> <Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=14062&title=Acute Spinal Cord Dysfunction Following COVID-19 Infection: A Case Report</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Abrams RMC, Safavi F, Tuhrim S, Navis A, Steinberg J, Shin SC. MRI negative myelopathy post mild SARS-CoV-2 infection: vasculopathy or inflammatory myelitis? J Neurovirol 2021; 27: 650-655. Eissa M, Abdelhady M, Alqatami H, Salem K, Own A, El Beltagi AH. 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