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<PublisherName>jmedicalcasereports</PublisherName>
<JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Volume 6; Issue 6</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>(Nov-Dec, 2025)</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
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<ArticleType>Medical Case Reports</ArticleType>
<ArticleTitle>Evaluation of Weight Loss and Comorbidities Improvements in Morbid Obese and Super Obese Patients After Laparoscopic Roux-en-Y Gastric Bypass: A Ten-Year Single Center Follow-Up</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1</FirstPage>
<LastPage>15</LastPage>
<AuthorList>
<Author>
<FirstName>Ida Francesca</FirstName>
<LastName>Gallo</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Kiara</FirstName>
<LastName>Sejfullai</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Chiara Isabella</FirstName>
<LastName>Miligi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Giuseppe</FirstName>
<LastName>Spagnolo</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Vincenzo</FirstName>
<LastName>Bruni</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
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<DOI/>
<Abstract>Aim: This study aims to evaluate the long-term efficacy and safety of Roux-en-Y gastric bypass (RYGB) in a cohort of patients from a high-volume center, focusing on outcomes over a ten-year-follow-up period. Methods: A retrospective analysis was conducted on patients who underwent laparoscopic RYGB at Belcolle Hospital between January 2010 and December 2013. Data were collected on weight loss, comorbidity resolution, and complications, with patients stratified into morbidly obese (MO) and super-obese (SO) groups. Results: Out of 149 patients, 71 met the ten-year follow-up criteria. At five years, mean body-mass index (BMI) was 27.8 kg/m², with a percentage of excess weight loss (%EWL) of 79.1%. By ten years, mean BMI increased to 31.8 kg/m², with %EWL decreasing to 61.1%. Comorbidity remission rates were high, with 93.7% of patients achieving diabetes remission. Complications included 11 reported events (15.5%), with no significant differences between MO and SO groups. The majority of patients experienced sustained weight loss and resolution of obesity-related comorbidities. Conclusions: RYGB is a safe and effective treatment for both morbidly and super-obese patients, achieving significant weight loss and improvement in comorbidities over a decade. These findings support expanding the indications for bariatric surgery, although further multicenter prospective studies are needed to mitigate biases inherent in single-center evaluations.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Roux-en-Y Gastric Bypass,RYGB,Long-Term Outcomes,Super-Obese Patients,Comorbidities Improvements,Diabetes Remission</Keywords>
<URLs>
<Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=16011&title=Evaluation of Weight Loss and Comorbidities Improvements in Morbid Obese and Super Obese Patients After Laparoscopic Roux-en-Y Gastric Bypass: A Ten-Year Single Center Follow-Up</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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</References>
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