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<PublisherName>jmedicalcasereports</PublisherName>
<JournalTitle>Frontiers in Medical Case Reports</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Volume 7; Issue 3</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>(May-Jun, 2026)</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>Medical Case Reports</ArticleType>
<ArticleTitle>Situational Syncope Across Diverse Triggers: A Diagnostic and Management challenge: Case Series</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1</FirstPage>
<LastPage>12</LastPage>
<AuthorList>
<Author>
<FirstName>Lydia</FirstName>
<LastName>Krexi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Sayed Irfan</FirstName>
<LastName>Kazi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Baher</FirstName>
<LastName>Hanna</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Celina</FirstName>
<LastName>Mark</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Tarek</FirstName>
<LastName>Fatrous</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Sara</FirstName>
<LastName>Ibzea</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Laszlo</FirstName>
<LastName>Rudas</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Attila</FirstName>
<LastName>Kardos</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
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<DOI/>
<Abstract>Situational syncope is a subtype of neurally mediated reflex syncope triggered by specific activities such as micturition, defaecation, coughing, swallowing, or laughter, but remains under-recognised in clinical practice. We present a case series of six adults with syncope or presyncope associated with diverse triggers, including laughter, micturition, motion sickness, defaecation, swallowing, and coughing, highlighting the heterogeneity of presentation.
All patients underwent targeted evaluation with electrocardiography and echocardiography, with selective use of tilt-table testing. No structural heart disease or sustained arrhythmia was identified, supporting a reflex mechanism in all cases. Management was conservative, focusing on trigger avoidance, lifestyle modification, and patient education, with no recurrence observed during follow-up.
This series emphasises the central role of detailed history-taking in establishing the diagnosis of situational syncope and avoiding unnecessary investigations. Recognition of both common and less well-described triggers, alongside an understanding of the underlying autonomic mechanisms, enables accurate diagnosis and effective patient-centred management. Increased awareness of situational syncope may improve clinical confidence, reduce diagnostic uncertainty, and optimise outcomes in patients presenting with transient loss of consciousness.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Syncope,Trigger,Situational Syncope,Lifestyle Advice</Keywords>
<URLs>
<Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=16267&title=Situational Syncope Across Diverse Triggers: A Diagnostic and Management challenge: Case Series</Abstract>
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<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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</References>
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