<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 1; Issue 1</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Jan-Feb, 2020)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Kienbock’s Disease: A Case Study</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>7</LastPage> <AuthorList> <Author> <FirstName>Lori</FirstName> <LastName>Burkow-Heikkinen</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Erin</FirstName> <LastName>Morency</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Kienbock’s disease is a relatively rare disorder where the blood supply to one of the small bones in the wrist is interrupted. The affected bone, the lunate, is one of eight small carpal bones that is in the middle at the base of the wrist and is responsible for wrist movement. This case study examines an otherwise healthy white 71 year old female with extreme wrist pain, initially diagnosed by the provider as tiny ganglion cysts in the ulnar tissue but later appropriately diagnose Kienbock’s left wrist with ulnar minus. This case study will study the care of the wrist using a 940nm near-infrared light emitting diode. Background: There is no cure for Kienbock’s disease, but prompt treatment can help preserve wrist function and relieve pain. Kienbock’s disease progresses through four stages; loss of blood flow, sclerosis of bone, breakdown of lunate bone, and finally the breakdown of the remaining bones of the hand (Allan et al., 2001). The rate of progression is varied from case to case. Objective: To evaluate the effects of the near infrared light emitting diode on inflammation and bone healing. Materials and method: This article investigates the role of near infrared light emitting diode on the sclerosis of the lunate carpal bone, stage one of Kienbock’s disease. A review of books, journals, PubMed, and physician notes Discussion: Using the near infrared light emitting diode (NIR LED), healing rate has increased, a decrease in inflammation, bone regeneration, and pain has minimized. The NIR LED gallium arsenide can be used as an adjunctive therapy for reduction for this progressive disease.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Kienbock,Osteonecrosis,Fusion,Arthroplasty,Sclerosis,Near Infrared light emitting diode,Phototherapy</Keywords> <URLs> <Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=6763&title=Kienbock’s Disease: A Case Study</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Allan CH, Joshi A, Lichtman DM. Kienbock’s disease: diagnosis and treatment. J Am Acad Orthop Surg 2001; 9: 128-136. Jagdeo J, Adams L, Brody N, Seigel D, Transcranial red and near infrared light transmission in cavdaveric model. PloSONE 2012; 7e47460. Burkow L, Stockwell N, Morency E, Sosa P. The use of near infrared light emitting diode in treating sports-related injuries: a review. Research 2014; 1: 1278. Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J. Effect of NASA Light –emitting diode irradiation on wound healing. J ClinLaser Med Surg 2001; 19: 305-314. Blum A, Zarqh O, Peleg A, Sirchan R, Blum N, Salameh Y, Ganaem M. Vascular inflammation and endothelial dysfunction in fracture healing. Am J Orthop 2012; 41: 87-91. Salate AC, Barbosa G, Gasper P, Koeko PU, Paizotto Na, Benze BG, Foschiani. Effect of In-Ga-Al-P diode laser irradiation on angiogenesis in patial ruptures of Achilles tendon in rats. Photomed Laser Surg 2005; 23: 470-475. Liu Y, Wang D, Wu X, Zhou J. Ischemia Injury: A New method accelerates bone healing in a rat tibia fracture model. BioMed Research International 2019: 1-10. Du YY, Zhao YX,Liu YP, LIU W, Wang MM, Yuan CM. Regulatory Tweak/Fn14 signaling pathways as a potent target for controlling bone loss. Biomed Pharmacother 2015; 70: 170-173. Ding ZC, Lin YK, Gan YK, Tang TT. Molecular pathogenesis of fracture nonunion. J Orthop Translat 2018; 14: 45-56. Mitchell UH, Mack GL. Low-level laser treatment with near infrared light increases venous nitric oxide levels acutely; a single-blind, randomized clinical trial efficacy. Am J Phys Med Rehabil 2013; 92: 151-156. Fahy N, Menzel U, Alini M, Stoddart MJ. Shear and dynamic compression modulates the inflammatory phenotype of human monocytes in vitro. Front Immunol 2019; 10: 383. Metzger CE, Gong S, Aceves M, Bloomfield SA, Hook MA. Osteocytes reflect a pro-inflammatory state following spinal cord injuryin rodent model. Bone 2019; 120: 465-475. Ramasamy SK, Kusumbe AP, WangL, Adams RH. Endothelial notch activity promotes angiogenesis and osteogenesis in bone. Nature 2014; 507: 376-380. Wu X, Ma Y, Chen H, Hao Z, Su N, Li X, Shen J, Wang H. Lysophosphatidic acid induces interleukin-6 and CXCL15 secretion from MLO-Y4 cells through activation of the LPA1 receptor and PKCand;theta; signaling pathway. Int Immunopharmacol 2019; 70: 1405664. Icer MA, Gezmen-Karadag M. The multiple functions and mechanisms of osteopontin. Clin Biochem 2018; 59: 17-24. Wang Y, Kim J, Chan A, Whyne C, Nam D. A two phase regulation of bone regeneration: IL-17F mediates osteoblastogenesis via C/EBP-B in vitro. Bone 2018; 116: 47-57. Fernandes KP, Alves AN, Nunes FD, Souza NH, Silva JA Jr, Bussadori SK, Ferrari RA. Effect of photobiomodulation on expression of IL-1B in skeletal muscle following acute injury. Laser Med Sci 2013; 28: 1043-1046. Watson EC, Adams RH. Biology of bone: The vasculature of the skeletal system. Cold Spring Harb Perspect Med 2018; 8. De Oliveira Goncalves JB, Buchaim DV, de Souza Bueno CR, Pomini KT, Barraviera B, Junior RSF, Andreo JC, de Castro Rodrigues A, Cestari TM, Buchain RL. Effects of low-level laser therapy on autogenous bone graft stabilized with a new heterologous fibrin sealant. J Photochem Photobiol B 2016; 162: 663-668. Pinheiro ALB, Soares LGP, da Silva ACP, Santos NRS, da Silva APLT, Neves BLRC, Soares AP, Silveira L Jr. Laser/LED phototherapy on the repair of tibial fracture treated with wire osteosynthesis evaluated by Raman spectroscopy. Laser Med Sci 2018; 33: 1657-1666. Tani A, Chellini F, Giannelli M, Nosi D, Zecchi-Orlandini S, Sassoli C. Red (635nm), Near-Infrared (808nm), and Violet-Blue (405nm) photobiomodulation potentially on human osteoblasts and mesenchymal stromal cells: a morphological and molecular in vitro study. Int J Mol Sci 2018; 19. Zein R, Selting W, Benedicenti S. Effect of low-level laser therapy on bone regeneration during osseointegration and bone graft. Photomed Laser Surg 2017; 35: 649-658. Frerix M, Kroger K, Szalay G, Muller-Ladner U, Tarner IH. Is osteonecrosis of the lunate bone underestimated feature of systemic sclerosis? A case series of nine patients and review of literature. Semin Arthritis Rheum 2016; 45: 446-454. Hong IT, Lee S, Jang GC, Kim G, Han SH Kienbock’s disease with non-negative ulnar variance: Treatment with combines radial wedge and shortening osteotomy. Orthopade 2019; 48: 96-101. Kim S, Eichenauer F, Asmus A Mutze S, Eisenschenk A, Honigmann P. Superselective angiography of the wrist in patients with Kienbock disease. BMC Musculoskelet Disord 2019; 20: 143.</References> </References> </Journal> </Article> </ArticleSet>