<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>jmedicalcasereports</PublisherName> <JournalTitle>Frontiers in Medical Case Reports</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 2; Issue 2</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>(Mar-Apr, 2021)</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>2021</Year> <Month>03</Month> <Day>30</Day> </PubDate> <ArticleType>Medical Case Reports</ArticleType> <ArticleTitle>Insulin Pump Therapy: Yesterday, Today and Tomorrow</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>1</FirstPage> <LastPage>6</LastPage> <AuthorList> <Author> <FirstName>David</FirstName> <LastName>Bell</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Edison</FirstName> <LastName>Goncalves</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Historically, CSII therapy counteracted the peaking and short action of a long-acting human insulin through short-acting insulin in pumps obtaining stable and steady insulin levels between meals. As better short-acting insulins became available, the efficacy of CSII improved. Recently, the availability of long-acting and “peakless” insulins reduced the need for CSII. However, with the availability of accurate sensors utilized in a closed loop algorithm in combination with CSII has resulted in resurgence of CSII use. In the future the ability to utilize glucagon or even pramlintide infusions in combination with insulin infusion may result in even better glycemic control and greater use of CSII.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Insulin Pumps,Long Acting Insulin,Short Acting Insulin,Compliance,Convenience,Basal Bolus Therapy</Keywords> <URLs> <Abstract>https://www.jmedicalcasereports.org/ubijournal-v1copy/journals/abstract.php?article_id=9589&title=Insulin Pump Therapy: Yesterday, Today and Tomorrow</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Bell DS and Ovalle F. Improved glycemic control with use of continuous subcutaneous insulin infusion compared with multiple insulin injection therapy. Endocr Pract 2000; 6: 357-360. 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